This involves a translocation . The student will see that part of Chromosome 9 is attached to Chromosome 22 (the Philadelphia chromosome). This moves beyond simple aneuploidy into structural mutations.
The best activities use actual microscope images of stained human chromosomes, not vector cartoons. Students need to see the subtle differences in banding patterns that distinguish Chromosome 4 from Chromosome 5, for example. Interactive Karyotype Activity
The final step—cutting and pasting—is the origin of the classic classroom activity. Today, the digitizes that cutting/pasting process, adding layers of feedback, scoring, and diagnostic reasoning. This involves a translocation